目的 研究长叶纽子果根(Ardisia virens Kurz var. annamensis Pitard.)的化学成分。方法 长叶纽子果根体积分数70%乙醇提取物采用硅胶柱、Sephadex LH-20、ODS、制备液相进行分离纯化,根据波谱信息鉴定所得化合物的结构。结果 在长叶纽子果根中分离得到10个化合物,分别鉴定为11-O-咖啡酸岩白菜素(1)、11-O-(3',4'-二甲基没食子酰基)岩白菜素(2)、11-O-乙酰岩白菜素(3)、岩白菜素-11-O-α-D-半乳吡喃糖苷(4)、百两金皂苷B(5)、朱砂根皂苷D(6)、朱砂根皂苷G(7)、(+)-丁香树脂酚(8)、丁香酸(9)、十八碳癸二烯酸-2,3-二羟丙基酯(10)。结论 化合物1~10为首次从该植物中分离得到。
Abstract
OBJECTIVE To study the chemical constituents from Ardisia virens Kurz var. annamensis Pitard. METHODS The 70% ethanol extract from A.virens was isolated and purified by silica, Sephadex LH-20, ODS and preparative HPLC, then the structures of obtained compounds were identified by physicochemical properties and spectral data. RESULTS Ten compounds were isolated and identified as 11-O-caffeoylbergenin(1),11-O-(3', 4'-dimethygalloyl)-bergenin(2), 11-O-acetyl bergenin(3), bergenin-11-O-α-D-galactopyranoside(4),ardisiacrispin B(5), ardisicrenoside D(6), ardisicrenoside G(7), (+)-syringaresinol(8), syringic acid(9), octadecadienoic acid-2,3-dihydroxypropyl ester(10). CONCLUSION All the compounds are isolated from this plant for the first time.
关键词
长叶纽子果 /
化学成分 /
岩白菜素衍生物 /
三萜皂苷 /
分离 /
鉴定
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Key words
Ardisia virens Kurz var. annamensis Pitard /
chemical constituent /
bergenin derivative /
triterpene saponins /
isolation /
identification
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中图分类号：
R284
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参考文献
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脚注
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基金
国家重点研发计划项目资助(2018YFC1708100);贵州科技计划项目资助([2019]5407号);贵州省基础科学重点项目黔科合基础项目资助([2019] 1402号)
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